X-ray Diffraction in Support of Patent Litigation

SynchXray LLC. offers x-ray powder diffraction measurements of materials and pharmaceutical compounds using conventional x-ray sources, synchrotron radiation, and neutron sources to assist clients involved in patent infringement litigation.

Our services include: 

  • Identification of primary and secondary phases present in samples.

  • Quantitative analysis of phase content.

  • Estimation of fractional crystallinity in crystalline/amorphous samples.

  • Pair-distribution function analysis of amorphous components.

  • Determination of whether or not specific compounds, or polymorphs, are present in an accused product.

  • Establishing the limits-of-detection for specific compounds and polymorphs.

  • Crystallite size distribution determinations.

  • Preparation of Expert Reports on our findings, responses to Expert Reports from opposing litigants.

  • Expert testimony at depositions and trial.


Quality Control and Assurance

Materials and Pharmaceutical Laboratories can benefit from x-ray diffraction using synchrotron sources during the process of product development:

SynchXray’s services include:

  • Rapid x-ray powder diffraction acquisition to assess phase purity and quality. The use of high-energy x-rays coupled with state-of-the-art area detectors allow crystalline diffraction patterns to be collected in only a few seconds per sample, allowing high sample throughput.

  • Accelerated sample aging studies can be performed under a wide range of temperature and humidity conditions.

  • Environmental sample chambers are available for investigations of sample stability against corrosion and harsh conditions.


Conventional Powder Diffraction Capabilities

SynchXray LLC now has in-house x-ray powder diffraction capabilities with the addition of a Rigaku Miniflex II diffractometer!

s-l1600.jpg
s-l640.jpg